Royal Flora formula is a live, non-mutated primary culture dormant in the capsule. It is not freeze-dried or fermented. It is activated by body fluids. With a shelf life of many years, Royal Flora does not need to be refrigerated.
Since transient SBOs were originally in natural foods that were consumed years ago, they were resistant to stomach acids and are capable of implanting, surviving, and metabolizing in all intestinal environments regardless of the quantity of harmful bacterial strains present or the pH of the gut. As organisms that used to be ingested with healthy raw organic food every day, they must be replenished daily.